Obstructive sleep apnea (OSA) is a sleep-related breathing disorder caused by physiologic obstruction of the airways that affects nearly 1 billion individuals worldwide. It is known to be strongly associated with cardiovascular and metabolic comorbidities and is especially common in patients with obesity.
In individuals with OSA and overweight or obesity, weight loss is the main lifestyle recommendation. Positive airway pressure (PAP) therapy is an available treatment option for OSA, with continuous positive airway pressure (CPAP) typically being the first-line choice. However, patient selection is particularly important for many of the more targeted strategies. As such, guidelines describe different treatments for the management of OSA.
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